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Professor Jorge Erusalimsky

Professor of Biomedical Sciences
Cardiff School of Sport & Health Sciences - PhD, FRSB

Overview

Born in Argentina, Jorge graduated in 1983 with a PhD in Biochemistry from the Hebrew University of Jerusalem. Following postdoctoral work with Nobel Laureate Cesar Milstein at the MRC Laboratory of Molecular Biology in Cambridge, UK, he held his first independent academic research position at King's College Medical School in London, where he pioneered work on megakaryocyte biology. In 1996 he joined University College London (UCL) as a Senior Lecturer in Medicine and was promoted to Reader in 2003. At UCL he initiated research on the cell and molecular biology of ageing. In 2006 Jorge was appointed to the Chair of Biomedical Sciences at Cardiff Metropolitan University. In Cardiff Jorge continues to develop research at the interphase between biology and medicine, with a focus on ageing and vascular diseases.

Jorge is a fellow of the Royal Society of Biology and serves on the Editorial Boards of Gerontology and Mechanisms of Aging and Disease. He has held many research grants from charities, industry and the public sector, and is currently a partner of the European Commission-funded FRAILOMIC consortium which is dedicated to discovering biomarkers of frailty.

Research Publications

International Consortium to Classify Ageing-related Pathologies (ICCARP) senescence definitions: achieving international consensus

Short, E., Huckstepp, R. T. R., Alavian, K., Amoaku, W. M. K., Barber, T. M., van Beek, E. J. R., Benbow, E., Bhandari, S., Bloom, P., Cota, C., Chazot, P., Christopher, G., Demaria, M., Erusalimsky, J. D., Ferenbach, D. A., Foster, T., Gazzard, G., Glassock, R., Jamal, N. & Kalaria, R. & 26 others, Kanamarlapudi, V., Khan, A. H., Krishna, Y., Leeuwenburgh, C., van der Linde, I., Lorenzini, A., Maier, A. B., Medina, R. J., Miotto, C. L., Mukherjee, A., Mukkanna, K., Murray, J. T., Nirenberg, A., Palmer, D. B., Pawelec, G., Reddy, V., Rosa, A. C., Rule, A. D., Shiels, P. G., Sheridan, C., Tree, J., Tsimpida, D., Venables, Z. C., Wellington, J., Calimport, S. R. G. & Bentley, B. L., 21 Feb 2025, In: GeroScience.

Research output: Contribution to journalArticlepeer-review

Defining an ageing-related pathology, disease or syndrome: International Consensus Statement

ICCARP, 21 Sept 2024, In: GeroScience.

Research output: Contribution to journalArticlepeer-review

Frailty Influences the Relationship between the Soluble Receptor for Advanced Glycation-End Products and Mortality in Older Adults with Diabetes Mellitus

Butcher, L., Carnicero, J. A., Pérès, K., Bandinelli, S., García-García, F. J., Artalejo, F. R., Rodriguez-Mañas, L. & Erusalimsky, J. D., 9 Apr 2024, In: Gerontology. 70, 6, p. 585-594 10 p.

Research output: Contribution to journalArticlepeer-review

High levels of soluble RAGE are associated with a greater risk of mortality in COVID-19 patients treated with dexamethasone

Butcher, L., Zaldua, J. C., Carnicero, J. A., Hawkins, K., Whitley, J., Mothukuri, R., Evans, P. A., Morris, K., Pillai, S. & Erusalimsky, J. D., 5 Nov 2022, In: Respiratory Research. 23, 1, 303.

Research output: Contribution to journalLetterpeer-review

DPP4 Promotes Human Endothelial Cell Senescence and Dysfunction via the PAR2-COX-2-TP Axis and NLRP3 Inflammasome Activation

Valencia, I., Vallejo, S., Dongil, P., Romero, A., San Hipólito-Luengo, Á., Shamoon, L., Posada, M., García-Olmo, D., Carraro, R., Erusalimsky, J. D., Romacho, T., Peiró, C. & Sánchez-Ferrer, C. F., Jul 2022, In: Hypertension. 79, 7, p. 1361-1373 13 p.

Research output: Contribution to journalArticlepeer-review

The use of the soluble receptor for advanced glycation-end products (sRAGE) as a potential biomarker of disease risk and adverse outcomes

Erusalimsky, J. D., 24 Apr 2021, In: Redox Biology. 42, 101958.

Research output: Contribution to journalArticlepeer-review

A robust machine learning framework to identify signatures for frailty: a nested case-control study in four aging European cohorts

on behalf of the FRAILOMIC initiative, 18 Feb 2021, In: GeroScience. 43, 3, p. 1317-1329 13 p.

Research output: Contribution to journalArticlepeer-review

Higher sRAGE Levels Predict Mortality in Frail Older Adults with Cardiovascular Disease

Butcher, L., Carnicero, J. A., Pérès, K., Colpo, M., Gomez Cabrero, D., Dartigues, J. F., Bandinelli, S., Garcia-Garcia, F. J., Rodríguez-Mañas, L. & Erusalimsky, J. D., 21 Jan 2021, In: Gerontology. 67, 2, p. 202-210 9 p.

Research output: Contribution to journalArticlepeer-review

Oxidative stress, telomeres and cellular senescence: What non-drug interventions might break the link?

Erusalimsky, J. D., 26 Feb 2020, In: Free Radical Biology and Medicine. 150, p. 87-95 9 p.

Research output: Contribution to journalReview articlepeer-review

Proceedings of the Canadian Frailty Network Workshop: Identifying Biomarkers of Frailty to Support Frailty Risk Assessment, Diagnosis and Prognosis. Toronto, January 15, 2018

Canadian Frailty Network, Jul 2019, In: Journal of Frailty and Aging. 8, 3, p. 106-116 11 p.

Research output: Contribution to journalArticlepeer-review

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