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Professor Barry McDonnell
Professor of Cardiovascular Physiology
Cardiff School of Sport & Health Sciences
Overview
I am an active clinical research scientist in the area of cardiovascular physiology, which helps inform my teaching, design, development, delivery and evaluation of several taught programmes. These programmes include BSc Biomedical Science, BSc Healthcare Science, HNC Biomedical Science, HND Biomedical Science, BSc Biomedical Science (Health, Exercise and Nutrition), BSc Human Nutrition and Dietetics, BSc Public Health Nutrition, BSc Complementary Healthcare and BSc Podiatry.
I currently lead the Vascular Physiology Research Group focused on cardiovascular physiology, ageing and disease. I am Principle Investigator for three clinical physiology research trials: (The ARCADE trial, investigating the impact of respiratory disease on arterial haemodynamics; the ACCT study, investigating the role of premature vascular ageing on blood pressure and cardiovascular risk in Collaboration with University of Cambridge; and the HIT-LVAD Trial in Columbia University, New York Presbyterian Hospital, investigating the impact of ventricular assist device implantation on vascular haemodynamics in patients with heart failure). In addition to my teaching commitments, I have undertaken supervision of a number of PhD studentships, 2 post-doctoral research officers, a research nurse and 1 Marie-Sklodowska Curie Action global research fellow over the past 6 years in order to develop the group's research theme. The research group use a number of physiological testing procedures to underpin our research (blood sampling, cardiac structure and function, peripheral and central blood pressures, 24-hour blood pressure, large artery stiffness and microvascular flow pulsatility in the renal, cerebral and retinal vascular beds).
Research Publications
Abstract 4141946: Characterization of Cardiac, Autonomic, and Exercise Physiology in Patients with Long COVID
Suckow, E., Pierce, K., wulff, K., Arent, C., Kreye, S., Rosenberg, M., Sabin, K., Parker, H., Forbes, L., McDonnell, B., Stöhr, E. & Cornwell, W., 12 Nov 2024, In: Circulation. 150, Suppl_1Research output: Contribution to journal › Meeting Abstract › peer-review
Aortic-Femoral Stiffness Gradient and Cardiovascular Risk in Older Adults
Stone, K., Fryer, S., McDonnell, B., Meyer, M. L., Faulkner, J., Agharazii, M., Fortier, C., Pugh, C., Paterson, C., Zieff, G., Chauntry, A., Kucharska-Newton, A., Bahls, M. & Stoner, L., 7 Oct 2024, In: Hypertension. 81, 12, p. e185-e196Research output: Contribution to journal › Article › peer-review
May Measurement Month 2021: an analysis of blood pressure screening results from the UK and Republic of Ireland
Lee, S. C., Warrington, D., Beaney, T., Cockcroft, J. R., Pugh, C. J. A., Williams, A., Olding, T., Dolan, E., O'Brien, E., Hynes, L., Rabbitt, M., Cunnane, P., Schutte, A. E., Poulter, N. R. & McDonnell, B. J., 1 Jun 2024, In: European Heart Journal, Supplement. 26, Supplement_3, p. iii96-iii98Research output: Contribution to journal › Article › peer-review
Isolated systolic hypertension of youth – findings from the I24ABC consortium
Danninger, K., Weber, T., Wassertheurer, S., Protogerou, A., Sharman, J. E., Sala, E. R., Wilkinson, I., Hametner, B., Ortner, S., Mayer, C., Li, Y., Pascual, J. M., Argyris, A., Athanasopoulou, E., Karachalias, F., Mceniery, C., Stergiou, G., Gomes, M. A. M. & Mcdonnell, B., 1 May 2024, In: Journal of Hypertension. 42, Suppl 1, p. e9Research output: Contribution to journal › Article › peer-review
Hypertension phenotypes based on brachial and aortic 24hr systolic pressure and their association with hypertension phenotypes based on both brachial and aortic 24hr systolic pressure and their association with left ventricular hypertrophy: findings from the I24ABC consortium
Athanasopoulou, E., Weber, T., Wassertheurer, S., Sharman, J. E., Argyris, A., Sala, E. R., Jankowski, P., Muiesan, M. L., Giannattasio, C., Wilkinson, I., Hametner, B., Orter, S., Mayer, C., Li, Y., Pascual, J. M., Danninger, K., Karachalias, F., McEniery, C., Pucci, G. & Blacher, J. & 12 others, , May 2024, In: Journal of Hypertension. 42, Suppl 1, p. e201Research output: Contribution to journal › Meeting Abstract › peer-review
Noninvasive Estimation of Blood Pressure in HeartMate 3 Patients
Pinsino, A., Gaudig, A., Castagna, F., Mondellini, G. M., McDonnell, B. J., Stöhr, E. J., Cockcroft, J., Kormos, R. L., Sayer, G. T., Uriel, N., Naka, Y., Takeda, K., Yuzefpolskaya, M. & Colombo, P. C., 1 Feb 2024, In: ASAIO Journal. 70, 2, p. e18-e20Research output: Contribution to journal › Article › peer-review
Pharmacological modulation of vascular ageing: A review from VascAgeNet
Roth, L., Dogan, S., Tuna, B. G., Aranyi, T., Benitez, S., Borrell-Pages, M., Bozaykut, P., De Meyer, G. R. Y., Duca, L., Durmus, N., Fonseca, D., Fraenkel, E., Gillery, P., Giudici, A., Jaisson, S., Johansson, M., Julve, J., Lucas-Herald, A. K., Martinet, W. & Maurice, P. & 16 others, , 25 Nov 2023, In: Ageing Research Reviews. 92, 102122.Research output: Contribution to journal › Review article › peer-review
Exertional Cardiac and Pulmonary Vascular Hemodynamics in Patients With Heart Failure With Reduced Ejection Fraction
EDWARD, J. A., PARKER, H. U. G. H., STÖHR, E. J., MCDONNELL, B. J., O'GEAN, K., SCHULTE, M., LAWLEY, J. S. & CORNWELL, W. K., Sept 2023, In: Journal of Cardiac Failure. 29, 9, p. 1276-1284 9 p.Research output: Contribution to journal › Article › peer-review
Pulsatility and flow patterns across macro- and microcirculatory arteries of continuous-flow left ventricular assist device patients
Stöhr, E. J., Ji, R., Mondellini, G., Braghieri, L., Akiyama, K., Castagna, F., Pinsino, A., Cockcroft, J. R., Silverman, R. H., Trocio, S., Zatvarska, O., Konofagou, E., Apostolakis, I., Topkara, V. K., Takayama, H., Takeda, K., Naka, Y., Uriel, N., Yuzefpolskaya, M. & Willey, J. Z. & 2 others, , 10 Aug 2023, In: Journal of Heart and Lung Transplantation. 42, 9, p. 1223-1232 10 p.Research output: Contribution to journal › Article › peer-review
Blood flow kinetic energy is a novel marker for right ventricular global systolic function in patients with left ventricular assist device therapy
Akiyama, K., Colombo, P. C., Stöhr, E. J., Ji, R., Wu, I. Y., Itatani, K., Miyazaki, S., Nishino, T., Nakamura, N., Nakajima, Y., McDonnell, B. J., Takeda, K., Yuzefpolskaya, M. & Takayama, H., 16 May 2023, In: Frontiers in Cardiovascular Medicine. 10, 1093576.Research output: Contribution to journal › Article › peer-review