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Professor Barry McDonnell

Professor of Cardiovascular Physiology
Cardiff School of Sport & Health Sciences

Overview

I am an active clinical research scientist in the area of cardiovascular physiology, which helps inform my teaching, design, development, delivery and evaluation of several taught programmes. These programmes include BSc Biomedical Science, BSc Healthcare Science, HNC Biomedical Science, HND Biomedical Science, BSc Biomedical Science (Health, Exercise and Nutrition), BSc Human Nutrition and Dietetics, BSc Public Health Nutrition, BSc Complementary Healthcare and BSc Podiatry.

I currently lead the Vascular Physiology Research Group focused on cardiovascular physiology, ageing and disease. I am Principle Investigator for three clinical physiology research trials: (The ARCADE trial, investigating the impact of respiratory disease on arterial haemodynamics; the ACCT study, investigating the role of premature vascular ageing on blood pressure and cardiovascular risk in Collaboration with University of Cambridge; and the HIT-LVAD Trial in Columbia University, New York Presbyterian Hospital, investigating the impact of ventricular assist device implantation on vascular haemodynamics in patients with heart failure). In addition to my teaching commitments, I have undertaken supervision of a number of PhD studentships, 2 post-doctoral research officers, a research nurse and 1 Marie-Sklodowska Curie Action global research fellow over the past 6 years in order to develop the group's research theme. The research group use a number of physiological testing procedures to underpin our research (blood sampling, cardiac structure and function, peripheral and central blood pressures, 24-hour blood pressure, large artery stiffness and microvascular flow pulsatility in the renal, cerebral and retinal vascular beds).

Research Publications

Abstract 4141946: Characterization of Cardiac, Autonomic, and Exercise Physiology in Patients with Long COVID

Suckow, E., Pierce, K., wulff, K., Arent, C., Kreye, S., Rosenberg, M., Sabin, K., Parker, H., Forbes, L., McDonnell, B., Stöhr, E. & Cornwell, W., 12 Nov 2024, In: Circulation. 150, Suppl_1

Research output: Contribution to journalMeeting Abstractpeer-review

Aortic-Femoral Stiffness Gradient and Cardiovascular Risk in Older Adults

Stone, K., Fryer, S., McDonnell, B., Meyer, M. L., Faulkner, J., Agharazii, M., Fortier, C., Pugh, C., Paterson, C., Zieff, G., Chauntry, A., Kucharska-Newton, A., Bahls, M. & Stoner, L., 7 Oct 2024, In: Hypertension. 81, 12, p. e185-e196

Research output: Contribution to journalArticlepeer-review

May Measurement Month 2021: an analysis of blood pressure screening results from the UK and Republic of Ireland

Lee, S. C., Warrington, D., Beaney, T., Cockcroft, J. R., Pugh, C. J. A., Williams, A., Olding, T., Dolan, E., O'Brien, E., Hynes, L., Rabbitt, M., Cunnane, P., Schutte, A. E., Poulter, N. R. & McDonnell, B. J., 1 Jun 2024, In: European Heart Journal, Supplement. 26, Supplement_3, p. iii96-iii98

Research output: Contribution to journalArticlepeer-review

Isolated systolic hypertension of youth – findings from the I24ABC consortium

Danninger, K., Weber, T., Wassertheurer, S., Protogerou, A., Sharman, J. E., Sala, E. R., Wilkinson, I., Hametner, B., Ortner, S., Mayer, C., Li, Y., Pascual, J. M., Argyris, A., Athanasopoulou, E., Karachalias, F., Mceniery, C., Stergiou, G., Gomes, M. A. M. & Mcdonnell, B., 1 May 2024, In: Journal of Hypertension. 42, Suppl 1, p. e9

Research output: Contribution to journalArticlepeer-review

Hypertension phenotypes based on brachial and aortic 24hr systolic pressure and their association with hypertension phenotypes based on both brachial and aortic 24hr systolic pressure and their association with left ventricular hypertrophy: findings from the I24ABC consortium

Athanasopoulou, E., Weber, T., Wassertheurer, S., Sharman, J. E., Argyris, A., Sala, E. R., Jankowski, P., Muiesan, M. L., Giannattasio, C., Wilkinson, I., Hametner, B., Orter, S., Mayer, C., Li, Y., Pascual, J. M., Danninger, K., Karachalias, F., McEniery, C., Pucci, G. & Blacher, J. & 12 others, Stergiou, G., Gomes, M. A. M., McDonnell, B., de la Sierra, A., Piskorz, D., Agharazii, M., Bahous, S. A., Perl, S., Zhang, Y., Nemcsik, J., Gkaliagkousi, E. & Protogerou, A., May 2024, In: Journal of Hypertension. 42, Suppl 1, p. e201

Research output: Contribution to journalMeeting Abstractpeer-review

Noninvasive Estimation of Blood Pressure in HeartMate 3 Patients

Pinsino, A., Gaudig, A., Castagna, F., Mondellini, G. M., McDonnell, B. J., Stöhr, E. J., Cockcroft, J., Kormos, R. L., Sayer, G. T., Uriel, N., Naka, Y., Takeda, K., Yuzefpolskaya, M. & Colombo, P. C., 1 Feb 2024, In: ASAIO Journal. 70, 2, p. e18-e20

Research output: Contribution to journalArticlepeer-review

Pharmacological modulation of vascular ageing: A review from VascAgeNet

Roth, L., Dogan, S., Tuna, B. G., Aranyi, T., Benitez, S., Borrell-Pages, M., Bozaykut, P., De Meyer, G. R. Y., Duca, L., Durmus, N., Fonseca, D., Fraenkel, E., Gillery, P., Giudici, A., Jaisson, S., Johansson, M., Julve, J., Lucas-Herald, A. K., Martinet, W. & Maurice, P. & 16 others, McDonnell, B. J., Ozbek, E. N., Pucci, G., Pugh, C. J. A., Rochfort, K. D., Roks, A. J. M., Rotllan, N., Shadiow, J., Sohrabi, Y., Spronck, B., Szeri, F., Terentes-Printzios, D., Tunc Aydin, E., Tura-Ceide, O., Ucar, E. & Yetik-Anacak, G., 25 Nov 2023, In: Ageing Research Reviews. 92, 102122.

Research output: Contribution to journalReview articlepeer-review

Exertional Cardiac and Pulmonary Vascular Hemodynamics in Patients With Heart Failure With Reduced Ejection Fraction

EDWARD, J. A., PARKER, H. U. G. H., STÖHR, E. J., MCDONNELL, B. J., O'GEAN, K., SCHULTE, M., LAWLEY, J. S. & CORNWELL, W. K., Sept 2023, In: Journal of Cardiac Failure. 29, 9, p. 1276-1284 9 p.

Research output: Contribution to journalArticlepeer-review

Pulsatility and flow patterns across macro- and microcirculatory arteries of continuous-flow left ventricular assist device patients

Stöhr, E. J., Ji, R., Mondellini, G., Braghieri, L., Akiyama, K., Castagna, F., Pinsino, A., Cockcroft, J. R., Silverman, R. H., Trocio, S., Zatvarska, O., Konofagou, E., Apostolakis, I., Topkara, V. K., Takayama, H., Takeda, K., Naka, Y., Uriel, N., Yuzefpolskaya, M. & Willey, J. Z. & 2 others, McDonnell, B. J. & Colombo, P. C., 10 Aug 2023, In: Journal of Heart and Lung Transplantation. 42, 9, p. 1223-1232 10 p.

Research output: Contribution to journalArticlepeer-review

Blood flow kinetic energy is a novel marker for right ventricular global systolic function in patients with left ventricular assist device therapy

Akiyama, K., Colombo, P. C., Stöhr, E. J., Ji, R., Wu, I. Y., Itatani, K., Miyazaki, S., Nishino, T., Nakamura, N., Nakajima, Y., McDonnell, B. J., Takeda, K., Yuzefpolskaya, M. & Takayama, H., 16 May 2023, In: Frontiers in Cardiovascular Medicine. 10, 1093576.

Research output: Contribution to journalArticlepeer-review

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