Title
Visiting Professor
Qualifications
BSc (Hons) Biochemistry, London 1975
MB ChB Leicester 1980
MRCP (UK) 1984
FRCP 1997
FBPharmacolS 2005
Research Interests
Forearm venous occlusion plethysmography with infusion of drugs and vasoactive peptides into the brachial artery and dorsal hand veins
Study of the effects of vasoactive peptides : Angiotensin I, Angiotensin II, Bradykinin, Atrial Natriuretic Peptide, Substance P, Vasoactive Intestinal Polypeptide, Peptide YY, Pituitary Adenyl Cyclase Activating Polypeptide and Endothelin
Study of the effects of angiotensin, bradykinin and endothelin on sympathetic vascular tone in humans
Study of the effects of local ACE inhibition on the action of vasoactive peptides in the human forearm
Study of the effects of systemic angiotensin II receptor blockade on the action of angiotensin I, angiotensin II and bradykinin in the human forearm
Study of endothelial function in hypertensive patients, patients with insulin and non insulin dependent diabetes mellitus and patients with hyperlipidaemia
Study of the vascular effects of Nebivolol a novel beta receptor antagonist which may exert some of its activity via release of EDRF
Study of the effects of Icatabant a bradykinin receptor antagonist on forearm blood flow responses to intra-arterial bradykinin
Effect of antioxidants on endothelial function in normal healthy volunteers
Clinical Studies
Study of the effects of oral and intravenous Aspirin on prostacyclin and thromboxane production in man
Study of prostacyclin and thromboxane production in human essential hypertension
Double blind comparison of a novel vasodilator agent cicletinine with atenolol and placebo in human essential hypertension
Interaction between aspirin and GTN on bleeding time in man
The inhibition of constitutive and inducible nitric oxide synthase in patients with septicaemic shock
Genetic polymorphism of the ACE gene in diabetics with and without microalbuminuria
Responses to intra-arterial angiotensin I, II and bradykinin in normal healthy volunteers characterised for their ACE gene polymorphism
Effect of a bradykinin receptor antagonist icatibant on the hypotensive response to ACE inhibition
Effect of antioxidants on endothelial function in normal subjects and in subjects with hypercholesterolaemia
Effect of β2 adrenoceptor polymorphism on vascular responses to isoprenaline in hypertensive blacks and caucasians
Development of the technique of applanation tonometery and pulse wave analysis to study vascular stiffness as a novel cardiovascular risk factor and also to develop the technique as a non invasive method of assessing endothelial dysfunction in large populations at risk of CVD
Use of pulse wave analysis to study the vascular effects of insulin in diabetic and non diabetic subjects
Consultancy
Professor in Cardiology
Department of Cardiology
Wales Heart Research Institute
University of Wales College of Medicine
Heath Park
Cardiff CF14 XN
Visiting Professor
Department of Biomedical Engineering
Mcquarie University
Sydney Australia
Visiting Professor
Department of Cardiology
Columbia Presbyterian Hospital
New York
Membership of Professional Bodies
Medical Research Society
British Medical Association
International Society of Hypertension
British Hypertension Society
London Hypertension Society
British Hypertension Research Group
European Society of Internal Medicine
European Society of Hypertension
Microcirculation Research Society
American Society of Hypertension
British Pharmacological Society
European Association for the Study of Diabetes
Society of Physicians of Wales
Welsh Cardiac Society
European Council for Blood Pressure and Cardiovascular Research
British Society for Heart Failure
American Society for the Advancement of Science
Drug Information Association
The Blood Pressure Association
European Association of Clinical Pharmacology and Therapeutics (Secretary)
National Conference of University Professors
Association of Physicians of Great Britain
British Atherosclerosis Society
Research Profile
Papers
Cockcroft JR, Ritter JM, Allison DJ, Causon R, Brown MJ. Localisation of extra adrenal catecholamine secreting tumours by selective venous sampling and nuclear magnetic resonance scanning. Postgrad Med J 1987;63:451-453.
Barrow SE, Cockcroft JR, Dollery CT, Hickling NE, Ritter JM. Identification of 13, 14-dihydro-15-oxo-prostaglandin F2 in the circulation during infusions of bradykinin and prostaglandin E2 in man. Br J Pharmacol 1987;81:245-250.
Webb DJ, Benjamin N, Allen MJ, Brown J, O'Flynn M, Cockcroft JR. Vascular responses to local atrial natriuretic peptide infusion in man. Br J Clin Pharmacol 1988;26:245-251.
Benjamin N, Cockcroft JR, Collier J, Dollery CT, Ritter JM, Webb DJ. The effect of local converting enzyme inhibition on the vascular responses to angiotensin and bradykinin in the forearm resistance vessels in man. J Physiol 1989;412:543-555.
Cockcroft JR, Allen MJ, Benjamin N, Webb DJ. The effect of local angiotensin converting enzyme inhibition on the actions of atrial natriuretic peptide in the human forearm. J Hum Hypertens 1989;3:49-52.
Webb DJ, Benjamin N, Cockcroft JR, Collier JG. Augmentation of sympathetic venoconstriction by angiotensin II in human dorsal hand veins. Am J Hypertens 1989;2:721-723
Ritter JM, Cockcroft JR, Doktor HS, Beacham J, Barrow SE. Differential effect of aspirin on thromoboxane and prostaglandin biosynthesis in man. Br J Clin Pharmacol 1989;28:573-579.
Minuz P, Barrow, SE, Cockcroft, JR, & Ritter JM. Systemic and renal prostacyclin and thromboxane A2 biosynthesis in essential hypertension. J Hypertens 1989;7(6):S384-S385.
Cullen MJ, Cockcroft JR, Webb DJ. Bradykinin has no acute effect on the response to forearm blood flow to sympathetic stimulation in man Clin Sci 1990;78:399-401.
Gill JS, Yiargouy Y, Webb DJ, Meleagros L, Benjamin N, Chrysanthou BJ, Cockcroft JR, Causon RC, Camm AJ, Bloom SR. Peptide histidine valine: haemodynamic actions and pharmacokinetics in man differ from vacoactive intestinal peptide histidine methionine. Clin Sci 1990;78:487-492.
Minuz P, Barrow SE, Cockcroft JR, Ritter JM. Prostacyclin and thromboxane biosynthesis in mild essential hypertension. Hypertension 1990;15:469-474.
Minuz P, Barrow SE, Cockcroft JR, Ritter JM. Effects of nonsteroidal anti-inflammatory drugs on prostacyclin and thromboxane biosynthesis in patients with mild essential hypertension Br J Clin Pharmacol 1990;30:519-526.
Cockcroft JR, Webb DJ. Perindopril: a vascular friendly ACE inhibitor? Prescriber 1990;1:21-24.
Cockcroft JR, Clarke JG, Webb DJ. The effect of endothelin on resting blood flow and the response to sympathetically mediated vasoconstriction in the forearm of man. Br J Clin Pharmacol 1991;31:521-524.
Cockcroft JR, Ritter JM. Effects of aspirin and glyceryl trinitrate on bleeding time in man. Thromb Haemor Dis 1991;3:49-51.
Haynes WG, Clarke JG, Cockcroft JR, Webb DJ. Pharmacology of endothelin-1 in vivo in humans. J Cardiovasc Pharmacol 1991;17(Suppl 7):S284-S286.
Cockcroft JR. ACE inhibitors: today's drugs for hypertension? Prescriber 1991;20:23-25.
Warren JB, Cockcroft JR, Larkin SW, Kajekar R, Macrae A, Ghatei MA, Bloom SR. Pituitary adenylate cyclase activating polypeptide is a potent vasodilator in man. J Cardiovasc Pharmacol 1992;20:83-87.
Cockcroft JR. Non-Q wave myocardial infarction. Geriatr Med 1992;22:43-46.
Playford RJ, Benito-Orfila MA, Nandha KA, Nihoyannopoulos P, Cockcroft JR, Todd S, Domin J, Tatemoto K, Bloom SR, Calam J. Effects of peptide YY on the human cardiovascular system and pituitary: reversal of responses to vasoactive intestinal peptide. Am J Physiol 1992;263:E740-E747.
Chowienczyk PJ, Watts GF, Cockcroft JR, Ritter JM. Impaired endothelium-dependent vasodilation of forearm resistance vessels in hypercholesterolaemia Lancet 1992;340:1430-1432.
Cockcroft JR, Toy JL, Ritter JM. Lack of effect of ethyol (WR-2721) on forearm blood flow in healthy volunteers Eur J Clin Pharmacol 1993;44:103-104.
Steel JR, Cockcroft JR, Ritter JM. Blind drunk: an unusual cause of alcohol related loss of vision Postgrad Med J 1993;69:151-152.
Cockcroft JR. What drugs should patients take to prevent a second MI? MIMS Magazine Weekly 1993;20(No 15):33-34.
Ritter JM, Cockcroft JR, Sciberras DG, Goldberg MR. Clinical pharmacology of angiotensin and bradykinin in human forearm vasculature. J Hypertens 1993;11(Suppl 3):S59-S61.
Cockcroft JR, Chowienczyk PJ, Elliott TG, Ritter JM. Lack of effect of enalaprilat on the action of vasoactive intestinal polypeptide in the human forearm Br J Clin Pharmacol 1993;35:525-527.
Cockcroft JR, Keogh BE, Webb DJ, Ritter JM, Taylor KM. Responses to angiotensin with and without angiotensin converting enzyme inhibition in the left anterior descending canine coronary artery. Am J Cardiol 1993;21:1498-1499.
Chowienczyk PJ, Cockcroft JR, Ritter JM. Differential inhibition by NG monomethyl-L-arginine of vasodilator effects of acetylcholine and methacholine in human forearm vasculature. Br J Pharmacol 1993;110:736-738.
Cockcroft JR, Sciberras DG, Goldberg MR, Ritter JM. Differential effects of ACE inhibition and angiotensin II receptor blockade on responses to angiotensin and bradykinin in the human forearm. J Cardiovasc Pharmacol 1993;22:579-584.
Elliot TG, Cockcroft JR, Groop P-H, Morocutti A, Viberti GC, Ritter JM. Inhibition of nitric oxide synthesis in forearm vasculature of insulin dependent diabetics: blunted vasoconstriction in patients with microalbuminuria. Clin Sci 1993;85:687-693.
Barnes DG, Gibbons DRS, MacKenzie THM, McCullough WL, Clark AD, Millar JGB, Cockcroft JR, Elder MG, Hawkins DF. Phaeochromocytoma in late pregnancy; synchronous or delayed resection after delivery by caesarean section? J Obs Gynecol 1993;13:95-98.
Cockcroft JR, Chowienczyk PJ, Benjamin N, Ritter JM. Preserved endothelium-dependent vasodilation in patients with essential hypertension. N Engl J Med 1994;330:1036-1040.
Cockcroft JR, Ritter JM. Hypertensive heart disease: left ventricular hypertrophy and its regression with treatment Hosp Update 1994;20,No5 (Suppl):20-24.
Cockcroft JR, Chowienczyk PJ, Brett SE, Ritter JM. Effect of NG-monomethyl-l-arginine on kinin-induced vasodilation in the human forearm. Br J Clin Pharmacol 1994;38:307-310.
Chowienczyk PJ, Cockcroft JR, Ritter JM. Blood flow responses to intra-arterial acetylcholine in man: effects of basal flow and conduit vessel length. Clin Sci 1994;87:45-51.
Chowienczyk PJ, Watts GF, Cockcroft JR, Brett SE, Ritter JM. Sex differences in endothelial function in normal and hypercholesterolaemic subjects. Lancet 1994;344:305-306.
Cockcroft JR, Chowienczyk PJ, Brett SE, Bender N, Ritter JM. Effects of icatibant on bradykinin induced vasodilation in the human forearm Br J Clin Pharmacol 1994;38:317-321.
Chowienczyk PJ, Cockcroft JR, Ritter JM. Inhibition of cholinesterase selectively potentiates NG-monomethyl-l-arginine resistant actions of acetylcholine in human forearm vasculature. Clin Sci 1995;88:111-117.
Cockcroft JR, O'Kane K, Webb DJ. The local Renin-angiotensin system and vascular tone. J Pharmacol Ther 1995;65:193-213.
Kelion AD, Cockcroft JR, Ritter JM. Antiphospholipid syndrome in a patient with rapidly progressive fibrosing alveolitis. Postgrad Med J 1995;71:233-235.
Cockcroft JR, Chowienczyk PJ, Ritter JM. Hyperlipidaemia, hypertension and coronary heart disease. Lancet 1995;345:862-863.
Cockcroft JR, Chowienczyk PJ, Brett SE, Chen C, Wooding S, Dupont AG, Van Nueten L, Ritter JM. Nebivolol causes vasodilation in the human forearm vascular bed: evidence for an L-arginine/NO mediated mechanism. J Pharmacol Exp Ther 1995;274:1067-1071.
Cockcroft JR, Chowienczyk PJ, Brett SE, Mant TGK, Durnin C, Lynn F, Stevenson P, Ritter JM. The effect of HN-65021 on responses to angiotensin II in the human forearm vasculature. Br J Clin Pharmacol 1995;40:591-593.
Cockcroft JR, Chowienczyk PJ. Endothelial function and cardiovascular disease. Asean Heart J 1995;23:100-108
Makimattila S, Virkamaki A, Fagerudd J, Groop P-H, Cockcroft JR, Yki-Jarvinen H. Chronic hyperglycaemia impairs endothelial function and insulin sensitivity via different mechanisms in IDDM. Circulation 1996;94:1276-1282.
Cockcroft JR, Chowienczyk PJ. Beyond cholesterol reduction: is vitamin E the answer (Editorial). Heart 1996;76:293-294.
Ritter JM, Cockcroft JR. Angiotensin II blockade in the human forearm vascular bed. Blood Pressure 1996;(Supplement 2):67-70.
Cockcroft JR. Endothelial function and cardiovascular disease. Cardioguardian 1997;1:11-14.
Chowienczyk PJ, Watts GF, Wierzbicki AS, Cockcroft JR, Brett SE, Ritter JM. Preserved endothelial function with severe hypertriglyceridemia and low functional lipoprotein lipase activity. J Am Coll Cardiol 1997;29:964-968.
Gazis A, Page SA, Cockcroft JR. Vitamin E and cardiovascular protection in diabetes (Editorial). Br Med J 1997;314:1845-1846.
Cockcroft JR, Noon JP, Gardner-Medwin J, Bennett T. Adrenomedullin is a potent and long lasting voasodilator in human resistance and capacitance vessels. Br J Clin Pharmacol 1997;44:57-60.
Kneale BJ, Chowienczyk PJ, Cockcroft JR, Coltart DJ, Ritter JM. Vasoconstrictor sensitivity to noradrenaline and NG-monomethyl-L-arginine in men and women. Clin Sci 1997;93:513-518.
Cockcroft JR, Chowienczyk PJ, Brett SE, Chen C, Dupont AG, Van Nueten L, Wooding S, Ritter JM. Nebivolol vasodilates human forearm vasculature: Evidence for an L-arginine/NO mediated mechanism. Perfusion 1997;10:414-420.
Cockcroft JR, Wilkinson I, Webb DJ. The Trevor Howell Lecture. Age arterial stiffness and the endothelium. Age and Ageing 1997;26(suppl 4):53-60.
Brett SE, Cockcroft JR, Mant TGK, Ritter JM, Chowienczyk PJ. Haemodynamic effects of inhibition of nitric oxide synthase and of L-arginine at rest and during exercise. J Hypertens 1998;16:429-435.
Gazis A, Page SA, Cockcroft JR. ACE inhibitors, diabetes and cardiovascular disease (Editorial). Diabetalogia 1998;41:595-597.
Wilkinson IB, Cockcroft JR. Cholesterol, endothelial function and cardiovascular disease. Curr Opin Lipidol 1998;9:237-242.
Cockcroft JR, Wilkinson IB. Vessel wall properties and cardiovascular risk (Invited Commentary). J Hum Hypertens 1998;12:342-344.
Wilkinson IB, Fuchs S, Jansen I, Spratt J, Murray GD, Cockcroft JR, Webb DJ. The reproducibility of pulse wave velocity and augmentation index measured by pulse wave analysis. J Hypertens 1998;16:2079-2084.
Cockcroft JR, Brett SE, Chowienczyk PJ, Calzada K, Rice-Evans C, Ritter JM. Vasodilator effects of acetylcholine and sodium nitroprusside are not potentiated by dietary supplementation with anti-oxidants in healthy volunteers. Clin Sci 1998;(In Press).
Wilkinson IB, Cockcroft JR, Webb DJ. Pulse wave analysis and vascular stiffness. J Cardiovasc Pharmacol 1998;32(Suppl 3):S33-S37.
Gazis AG, White DJ, Page SR, Cockcroft JR. Effect of oral vitamin E (alpha-tocopherol) supplementation on vascular endothelial function in type 2 diabetes mellitus. Diabet Med 1999;16:304-311.
Westerbacka J, Vehkavaara S, Bergholm R, Wilkinson I, Cockcroft J, Yki-Jarvinen H. Marked resistance of the ability of insulin to decrease wave reflection in the aorta characterises human obesity. Diabetes 1999;48:821-827.
Cockcroft JR Restoring endothelial function in atherogenesis. Trend Cardiol Vasc Dis 1999;1(No 5):21-24.
Westerbacka J, Wilkinson I, Utriainen T, Vehavaara S, Cockcroft J, Yki-Jarvinen H. Diminished wave reflection in the aorta: a novel physiological action of insulin. Hypertension 1999;33:1118-1122.
Kneale BJ, Chowienczyk PJ, Brett SE, Cockcroft JR, Ritter JM. Forearm vasoconstriction to noradrenaline and monomethylarginine in essential hypertension. Clin Sci 1999;97:277-282.
Wilkinson IB, MacCallum H, Cockcroft JR, Webb DJ, Megson IL. Vitamin C reduces arterial stiffness and platelet aggregation in humans. J Cardiovas Pharmacol 1999;34:690-693.
Cockcroft JR. Nebivolol: More than just aNOther beta blocker? Prescriber 1999;10(No 16):25-30.
Wilkinson IB, Megson IL, MacCallum H, Sogo N, Cockcroft JR, Webb DJ. Oral vitamin C reduces arterial stiffness and platelet aggregation in humans. J Cardiovasc Pharmacol. 1999;34(5):690-693
Blackman DJ, Morris-Thurgood JA, Ellis GR, Atherton JJ, Cockcroft JR, Lewis MJ, Frenneaux MP. Endothelium-derived nitric oxide contributes to the regulation of venous tone in man. Circulation 2000;101:165-170.
Cockcroft JR, Webb DJ, Wilkinson IB. Arterial stiffness, hypertension and diabetes mellitus. J Hum Hypertens 2000;14:377-380.
Candy G, Samani NJ, Norton G, Woodwiss A, Radevski I, Wheatley A, Cockcroft JR, Hall IP. Association analysis of β2 adrenoceptor polymorphisms with hypertension in a black African population. J Hypertens 2000;18:167-172.
Wilkinson IB, MacCallum H, Flint L, Cockcroft JR, Newby DE, Webb DJ. The influence of heart rate on central arterial pressure and augmentation index. J Physiol 2000;525:263-270.
Wilkinson IB, Webb DJ, Cockcroft JR. Isolated systolic hypertension: a radical rethink (Editorial). Br Med J 2000;320:1685.
Wilkinson IB, MacCallum H, Rooijmans DF, Murray GD, Cockcroft JR, McKnight JA, Webb DJ. Increased augmentation index and systolic stress in subjects with type 1 diabetes mellitus. Quart J Med 2000;93:441-448.
Millasseau SC, Bland JE, Kelly RP, Prasad K, Cockcroft JR, Ritter JM, Chowienczyk PJ. Non-invasive assessment of the digital volume pulse. Comparison with the peripheral pressure pulse. Hypertension 2000;36:952-956.
Cockcroft JR, Gazis AG, White DJ, Wheatley A, Dewar J, Hall IP, Noon JP. β2 adrenoceptor polymorphism determines vascular reactivity in humans. Hypertension 2000;36:371-375.
Smith J, Page M, John R, Wheeler M, Cockcroft JR, Scanlon M, Davies J. Augmentation of central arterial pressure in mild primary hyperparathyroidism. J Clin Endocrinol Metab 2000;85:3515-3519.
Cockcroft JR, Wilkinson IB. Large arterial stiffness: an important therapeutic target. J Hum Hypertens 2000;14:533-535.
Wilkinson IB, Cockcroft JR. Mind the Gap: Pulse pressure, cardiovascular risk, and isolated systolic hypertension. Am J Hypertens 2000;13:1315-1317.
Smith JC, Bennett S, Evans LM, Kynaston HG, Parmar M, Mason MD, Cockcroft JR, Scanlon MF, Davies JS. The effects of induced hypogonadism on arterial stiffness, body composition, and metabolic parameters in males with prostate cancer. J Clin Endocrinol Metab. 2001;86:4261-7.
Cockcroft JR, Wilkinson IB, Yki-Jarvinen H. Multiple risk factor reduction in type 2 diabetes an opportunity not to be missed. Diabet Obes Metab 2001;3:1-8.
Wilkinson IB, MacCallum H, Hupperetz PC, van Thoor CJ, Cockcroft JR, Webb DJ. Changes in central pressure waveform and pulse pressure in response to angiotensin II and noradrenaline in man. J Physiol 2001;530:541-550.
Wilkinson IB, Megson IL, MacCallum H, Rooijmans DF, Johnson SM, Boyd J, Cockcroft JR, Webb DJ. Acute methionine loading does not alter arterial stiffness in man. J Cardiovasc Pharmacol 2001;37:1-5.
Nightingale AK, James P, Morris-Thurgood JA, Harrold F, Tong R, Jackson S, Cockcroft JR, Frenneaux MP. Evidence against oxidative stress as the mechanism of endothelial dysfunction in the methionine model. Am J Physiol 2001;280:H1334-H1339.
Cockcroft JR. Patient empowerment: A new partnership for the future (Editorial). Br J Cardiol 2001;8:273-275.
Hall IR, Tyrrell S, Wilkinson IB, Cockcroft JR. Self referral multiple cardiovascular risk factor assessment clinic: The Cardiff experience. Br J Cardiol 2001;8:303-310.
Wilkinson IB, McEniery CM, Bongaerts KH, MacCallum H, Webb DJ, Cockcroft JR. Adrenomedullin (ADM) in the human forearm vascular bed: effect of neutral endopeptidase inhibition and comparison with proadrenomedullin NH2-terminal 20 peptide (PAMP). Br J Clin Pharmacol 2001;52:159-164.
Smith J, Wilkinson IB, Cockcroft JR, Scanlon M, Davies J. Effects of androgen deprivation therapy on vascular compliance, body composition and metabolic parameters in males with prostate cancer. J Clin Endocrin Metab 2001;86:4261-4267
Wilkinson IB, Hall IR, Tyrrell S, Franklin SS, Cockcroft JR. Pulse pressure
amplification explains why diastolic pressure predicts risk in younger
subjects. Hypertension 2001;38(6):1461-1466.
Smith JC, Evans LM, Wilkinson IB, Goodfellow J, Cockcroft JR, Scanlon MF, Davies JS. Effects of GH replacement on endothelial function and large-artery stiffness in GH-deficient adults: a randomised, double-blind, placebo-controlled study. Clinical Endocrinology 2002;56(4):493-501.
Wilkinson IB, MacCallum H Cockcroft JR, Webb DJ. Inhibition of basal nitric oxide synthesis increases aortic augmentation index and pulse wave velocity in vivo. Br J Clin Pharmacol 2002;53(2):189-192.
Wilkinson IB, Qasem A, McEniery CM, Webb DJ, Avolio AP, Cockcroft JR. Nitric Oxide regulates local arterial distensibility in vivo. Circulation 2002;105:213-217
Wilkinson IB, Hall IR, MacCallum H, Mackenzie IS, McEneiry CM, van der Arend JB, Shu YE, MacKay LS, Webb DJ, Cockcroft JR. Pulse wave analysis – clinical evaluation of a non-invasive, widely applicable method for assessing endothelial function. Arterioscler Thromb and Vasc Biol 2002; 22:147-152.
Mackenzie IS, Wilkinson IB, Cockcroft JR. Assessment of arterial stiffness in clinical practice. Quart J Med 2002;95:67-74.
Wilkinson IB, Prasad K, Hall IR, Thomas A, MacCallum H, Webb DJ, Frenneaux MP, Cockcroft JR. Increased central pulse pressure and augmentation index in subjects with hypercholesterolaemia. J Am Coll Cardiol 2002;39:1005-1011.
Van Bortel LM, Duprez D, Starmans-Kool MJ, Safar ME, Giannattasio C, Cockcroft J, Kaiser DR, Thuillez C. Clinical applications of arterial stiffness, task force III: Recommendations for user procedures. Am J Hypertens 2002;15:445-452.
Cockcroft JR, Wilkinson IB. Arterial stiffness and pulse contour analysis: an age old concept revisited. Clin Sci 2002;103:379-380.
Schmitt M, Blackman DJ, Middleton GW, Cockcroft JR, Frenneaux MP. Assessment of venous capacitance. Radionuclide plethysmography: methodolgy and research applications. Br J Clin Pharmacol 2002;54:565-576.
Wilkinson IB, Mohammad NH, Tyrrell S, Hall IR, Webb DJ, Paul VE, Levy T, Cockcroft JR. Heart rate dependency of pulse pressure amplification and arterial stiffness. Am J Hypertens 2002;15:24-30.
Klocke R, Cockcroft JR, Taylor GJ, Hall IR, Blake DR. Arterial stiffness and central blood pressure as determined by pulse wave analysis in rheumatoid arthritis. Ann Rheum Dis 2003;62:414-418.
Cockcroft JR, McEniery CM, Wilkinson IB. Pseudohypertension of youth: too much of a good thing? Am J Hypertens 2003;16:262-264.
McEniery CM, Qasem A, Avolio AP, Cockcroft JR, Wilkinson IB. Endothelin-1 regulates arterial pulse-wave velocity in vivo. J Am Coll Cardiol 2003:42:1975-1981
Smith JC, Lane H, Evans LM, Cockcroft JR, Scanlon MF, Davies JS. The effects of depot long-acting analog (sandostatin LAR) on central aortic pressure and arterial stiffness in acromegaly. J Clin Endocrinol Metab 2003;88:2556-2561.
Schmitt M, Cockcroft JR, Frenneaux MP. Modulation of the natriuretic peptide system from bench to bedside? Key elements, basic principles, therapeutic challenges. Clin Sci 2003;105:141-160.
Schmitt M, Gunaruwan P, Payne N, Lee L, Broadley AJ, Taylor J, Nightingale AK, Cockcroft JR, Struthers AD, Tyberg JV, Frenneaux MP. Atrial natriuretic peptide regulates regional vascular volume and venous tone in humans. Arterioscler Thromb Vasc Biol 2003;23:1833-1838.
Westerbacka J, Tamminen M, Cockcroft J, Yki-Jarvinen H. Comparison of in vivo effects of nitroglycerine and insulin on the aortic pressure wave form. Eur J Clin Invest 2004;34:1-8.
McEniery CM, Cockcroft JR, Wilkinson IB. Systolic hypertension of youth: young men with an age old problem? Heart Failure & Hypertension Abstracts 2004;32:4-7.
Wilkinson IB, Cockcroft JR. Birth weight, arterial stiffness and blood pressure: in search of a unifying hypothesis. Int J Epidemiol 2004;33:161-162.
Cockcroft JR. Nebivolol: a review. Expert Opin Pharmacother 2004;5:893-899.
Schmitt M, Gunaruwan P, Payne N, Lee L, Broadley AJ, Taylor J, Nightingale AK, Cockcroft JR, Struthers AD, Tyberg JV, Frenneaux MP. The effects of exogenous and endogenous natriuretic peptides on forearm vascular function in patients with chronic heart failure: selective preservation of venous ANP responsiveness. Arterioscler Thromb Vasc Biol 2004;24:911-917.
Yasmin, McEniery CM, Wallace S, Mackenzie IS, Cockcroft JR, Wilkinson IB. C- reactive protein is associated with arterial stiffness in apparently healthy individuals. Arterioscler Thromb Vasc Biol 2004;24:969-974.
Schmitt M, Qasem A, McEniery CM, Wilkinson IB, Tatarinoff V, Noble K, Klemes J, Payne N, Frenneaux MP, Avolio AP, Cockcroft JR. The role of natriuretic peptides in the regulation of conduit artery distensibility Am J Physiol 2004;287:H1167-H1171
Sharman JE, Gunaruwan P, Knez WL, Schmitt M, Marsh SA, Wilson GR, Cockcroft JR, Coombes JS. Alpha-lipoic acid does not acutely affect resistance and conduit artery function or oxidative stress in healthy men. Br J Clin Pharmacol 2004;58:243-248.
Sharman JE, Cockcroft JR, Coombes JS. Cardiovascular implications of exposure to automotive pollution during exercise Q J Med 2004;97:637-643.
McEniery CM, Wilkinson IB, Qasem A, Schmitt M, Webb DJ, Avolio AP, Cockcroft JR. Nebivolol reduces arterial stiffness in vivo. Hypertension 2004;44:305-310.
Sharman JE, Cockcroft JR. Prognostic power of exercise haemodynamics: significance of the central pressure waveform. Bulletin Br Soc Cardiovasc Res
2004;17:4-9.
Wilkinson IB, Franklin SS, Cockcroft JR. Nitric oxide and the regulation of large artery stiffness: from physiology to pharmacology. Hypertension 2004;44:112-116.
Wierzbicki AS, Chowienczyk PJ, Cockcroft JR, Brett SE, Watts GF, Jenkins BS, Ritter JM. Cardiovascular risk factors and endothelial dysfunction. Clin Sci
2004;107:609-615.
Yasmin Y, McEniery CM, Dharkam Z, Wallace S, Pusalkar P, Ashby M, Cockcroft JR, Wilkinson IB. Serum metalloproteinase-9 is associated with arterial stiffness. Arterioscler Thromb Vasc Biol 2005;25:372-378.
Cockcroft JR, Deanfield J, Donald A, Ferranini E, Halcox J, Lusher TF, Mancia G, Natali A, Oliver JJ, Pessina AC, Rizzoni D, Rossi GP, Salvetti A, Spieker LE, Taddei S, Webb DJ. Endothelial function and dysfunction. Part II: Association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial factors of the European Society of Hypertension. J Hypertension 2005;23:233-246.
Schmitt M, Avolio AP, Qasem A, McEniery CM, Butlin M, Wilkinson IB, Cockcroft JR. Basal nitric oxide locally modulates human iliac artery function in vivo. Hypertension 2005:46:227-231.
McEniery CM, Yasmin, Wallace S, Maki-Petaja K, McDonnell B, Sharman JE, Retallick C, Franklin SS, Brown MJ, Lloyd RC, Cockcroft JR, Wilkinson IB. Increased stroke volume and arterial stiffness contribute to isolated systolic hypertension in young subjects: The Enigma Study. Hypertension 2005:46:221-226
McEniery CM, Yasmin, Hall IR, Qasem A, Wilkinson IB, Cockcroft JR. Normal vascular ageing: differential effects on wave reflection and aortic pulse wave velocity. The Anglo Cardiff Collaboration Trial (ACCT I). J Am Coll Cardiol 2005;46:1753-1760.
Cockcroft JR, Wilkinson IB, Evans LM, McEwan P, Peters JR, Davies JS, Scanlon MF, Currie CJ. Pulse pressure predicts cardiovascular risk in patients with type 2 diabetes mellitus. Am J Hypertens 2005;18:1463-1467.
Williams PC, Coffey MJ, Coles B, Sanchez S, Morrow JD, Cockcroft JR, Lewis MJ, O'Donnell VB. In vivo aspirin supplementation inhibits platelet nitric oxide consumption. Blood 2005;106:2737-2743
Sharman JE, McEniery CM, Campbell R, Coombes JS, Wilkinson IB, Cockcroft JR. The effect of exercise on large artery haemodynamics in healthy young men. European J Clin Invest 2005;35(12):738-744
Williams PC, Coffey MJ, Coles B, Sanchez, Morrow JD, Cockcroft JR, Lewis MJ, O'Donnell VB. In vivo aspirin supplementation inhibits nitric oxide consumption by human platelets. Blood 2005;106(8):2737-2743
Brunner H, Cockcroft JR, Deanfield J, Donald A, Ferrannini E, Halcox J, Kiowski W, Luscher TF, Mancia G, Natali A, Oliver JJ, Pessina AC, Rizzoni D, Rossi GP, Salvetti A, Spieker LE, Taddei S, Webb DJ. Endothelial function and dysfunction. Part II: Association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European Society of Hypertension. J Hypertens 2005;23(2):233-246
Yasmin, Wallace S, McEniery CM, Dhakham Z, Pusalkar P, Maki-Petaja K, Ashby MJ, Cockcroft JR, Wilkinson IB. Matrix metalloproteinase-9 (MMP-9), MMP-2, and serum elastase activity are associated with systolic hypertension and arterial stiffness. Arteriosclerosis Thrombosis and Vascular Biology 2005;25(2):372-378
Sharman JE, McEniery CM, Campbell RI, Coombes JS, Wilkinson IB, Cockcroft JR. The effect of exercise on large artery haemodynamics in healthy young men. Eur J Clin Invest 2005;35(12):738-44
Cockcroft JR. Exploring vascular benefits of endothelium-derived nitric oxide. Am J Hypertens 2005;18(12 Pt 2):177S-183S
Yasmin, O'Shaughnessy KM, McEniery CM, Cockcroft JR, Wilkinson IB. Genetic variation in fibrillin-1 gene is not associated with arterial stiffness in apparently healthy individuals. J Hypertens 2006;24(3):499-502
Wilkinson IB, McEniery CM, Cockcroft JR Atenolol and cardiovascular risk: an issue close to the heart. Lancet 2006;25:367(9511):627-9
Horan M, Newsway V, Yasmin, Lewis MD, Easter TE, Rees DA, Mahto A, Millar. DS, Procter AM, Scanlon MF, Wilkinson IB, Hall IP, Wheatley A, Blakey J, Bath PM, Cockcroft JR, Krawczak M, Cooper DN. Genetic variation at the growth hormone (HG1) and growth hormone receptor (GHR) loci as a risk factor for hypertension. Hum Gen 2006;119(5):527-40
Yasmin, O'Shaughnessy KM, McEniery CM, Cockcroft JR, Wilkinson IB. Genetic variation in fibrillin-1 gene is not associated with arterial stiffness in apparently healthy individuals. J Hypertens 2006;24(3):499-502
McEniery CM, Wallace S, Mackenzie IS, McDonnell B, Yasmin, Newby DE, Cockcroft JR, Wilkinson IB. Endothelial function is associated with pulse pressure, pulse wave velocity, and augmentation index in healthy humans. Hypertension 2006;48(4):602-608
Laurent S, Cockcroft J, Van Bortel L, Boutouyrie P, Giannattasio C, Hayoz D, Pannier B, Vlachopoulos C, Wilkinson IB, Struiker-Boudier H. Expert consensus document on arterial stiffness: methodological issues and clinical applications. European Heart Journal 2006;27(21):2588-2605
Horan M, Newsway V, Lewis YMD, Easter TE, Rees DA, Mahto A, Millar DS, Procter AM, Scanlon MF, Wilkinson IB, Hall IP, Wheatley A, Blakey J, Bath PMW, Cockcroft JR, Krawczak M, Cooper DN. Genetic variation at the growth hormone (GH1) and growth hormone receptor (GHR) loci as a risk factor for hypertension and stroke. Human Genetics 2006;119(5):527-540
Yasmin, O'Shaughnessy KM, McEniery CM, Cockcroft JR, Wilkinson IB
Genetic variation in fibrillin-1 gene is not associated with arterial stiffness in apparently healthy individuals. J Hypertens 2006;24(3):499-502
Dhakam Z, McEniery CM, Yasmin, MCeniery CM, Brown MJ, Cockcroft JR, Wilkinson IB. Differential effects on central blood pressure and aortic pulse wave velocity. Am J Hypertens 2006;19(2):214-219
Yasmin, McEniery CM, O'Shaughnessy KM, Harnett P, Arshad A, Wallace S, Maki-Petaja K, McDonnell B, Ashby MJ, Brown J, Cockcroft J, Wilkinson IB. Variation in the human matrix metalloproteinase-9 gene is associated with arterial stiffness in healthy individuals. Arterioscler Thromb Vasc Biol 2006;26(8):1799-805
Lane HA, Grace F, Smith JC, Morris K, Cockcroft J, Scanlon MF, Davies JS
Impaired vasoreactivity in bodybuilders using androgenic anabolic steroids. Eur J Clin Invest 2006;36(7):483-8
Pederson ME, Cockcroft JR. The latest generation of beta-blockers: new pharmacologic properties. Curr Hypertens Rep 2006;8(4):279-86
McEniery CM, Wallace S, Mackenzie IS, McDonnell B, Yasmin, Newby DE, Cockcroft JR, Wilkinson IB. Endothelial function is associated with pulse pressure, pulse wave velocity, and augmentation index in healthy humans. Hypertension 2006;48(4):602-8
Laurent S, Cockcroft J, Van Bortel L, Boutouyrie P, Giannattasio C, Hayoz D, Pannier B, Vlachopoulos, C, Wilkinson I, Struijker-Boudier H; European Network for Non-invasive Investigation of Large Arteries. Expert consensus document on arterial stiffness:methodological issues and clinical applications. Eur Heart J 2006;27(21):2588-605
McEniery CM, Wilkinson IB, Cockcroft JR. Systolic hypertension in young adults: spurious definition of a genuine condition. J Hypertens 2006;24(11):2316-7
Mason RP, Cockcroft JR. Targeting nitric oxide with drug therapy. J Clin Hypertens (Greenwich) 2006;8(12 Suppl 4):40-52
Pederson ME, Cockcroft JR. The vasodilatory beta-blockers. Current Hypertension Reports 2007;(4):69-277
Wallace SML, Yasmin, McEniery CM, Maki-Petaja KM, Both AD, Cockcroft JR, Wilkinson IB. Isolated systolic hypertension is characterized by increased aortic stiffness and endothelial dysfunction. Hypertension 2007(1):228-233
Sharman JE, McEniery CM, Dhakam ZR, Coombes JS, Wilkinson IB, Cockcroft JR
Pulse pressure amplification during exercise is significantly reduced with age and hypercholesterolemia. J Hypertens 2007;25(6):1249-1254
Sabit R, Bolton CE, Edwards PH, Pettit RJ, Evans WD, McEniery CM, Wilkinson IB, Cockcroft JR, Shale DJ. Arterial stiffness and osteoporosis in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine 2007;175(12):1259-1265
Smith JC, McDonnell B, Retallick C, McEniery C, Carey C, Davies JS, Barrett T, Cockcroft JR, Paisey R. Is arterial stiffening in Alstrom syndrome linked to the development of cardiomyopathy? European Journal of Clinical Investigation 2007;37(2):99-105
McEniery CM, Cockcroft JR. Does arterial stiffness predict atherosclerotic coronary events? Adv Cardiol 2007;44:160-72
Wilkinson I, Cockcroft JR. Cholesterol, lipids and arterial stiffness. Adv Cardiol 2007;44:261-77
Smith JC, McDonnell B, Retallick C, McEniery C, Carey C, Davies JS, Barrett T, Cockcroft JR, Paisey R. Is arterial stiffening in Alström syndrome linked to the development of cardiomyopathy? Eur J Clin Invest 2007;37(2):99-105
Sabit R, Bolton CE, Edwards PH, Pettit RJ, Evans WD, McEniery CM,Wilkinson IB, Cockcroft JR, Shale DJ. Arterial stiffness and osteoporosis in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007;175(12):1259-65
Wallace SM, Yasmin, McEniery CM, Mäki-Petäjä KM, Booth AD, Cockcroft JR, Wilkinson IB, Cockcroft JR, Shale DJ. Isolated systolic hypertension is characterized by increased aortic stiffness and endothelial dysfunction. Hypertension 2007;50(1):228-33
Sharman JE, McEniery CM, Dhakam ZR, Coombes JS, Wilkinson IB, Cockcroft JR Pulse pressure amplificiation during exercise is significantly reduced with age and hypercholesterolemia. J Hypertens 2007;25(6):1249-54
Pedersen ME, Cockcroft JR. The vasodilatory beta-blockers. Curr Hypertens Rep. 2007;9(4):269-77
Cockcroft JR. ACE inhibition in hypertension: focus on perindopril. Am J Cardiovasc Drugs 2007;7(5):303-17
Cockcroft J. A review of the safety and efficacy of nebivolol in the mildly hypertensive patient. Vasc Health Risk Manag 2007;3(6):909-17
Kinra S, Rameshwar Sarma KV, Ghafoorunissa, Mendu VV, Ravikumar R, Mohan V, Wilkinson IB, Cockcroft JR, Davey Smith G, Ben-Shlomo Y. Effect of integration of supplemental nutrition with public health programmes in pregnancy and early childhood on cardiovascular risk in rural Indian adolescents: long term follow-up of Hyderabad nutrition trial. British Medical Journal 2008;337(7667):a605
McEinery CM, McDonnell B, Munnery M, Wallace SM, Rowe CV, Cockcroft JR, Wilkinson IB. Central pressure: Variability and impact of cardiovascular risk factors - The Anglo-Cardiff Collaborative Trial II. Hypertension 2008;51(6);1476-1482
Sharman JE, McEiniery CM, Campbell R, Pusalkar P, Wilkinson IB Coombes JS, Cockcroft JR. Nitric oxide does not significantly contribute to changes in pulse pressure amplification during light aerobic exercise. Hypertension 2008;51(4):856-861.
Sharman JE, McEniery CM, Campbell R, Pusalkar P, Wilkinson IB, Coombes JS, Cockcroft JR. Nitric oxide does not significantly contribute to changes in pulse pressure amplification during light aerobic exercise. Hypertension 2008;51(4):856-61
McEniery CM, Yasmin, McDonnell B, Munnery M, Wallace SM, Rowe CV, Cockcroft JR, Wilkinson IB; Anglo-Cardiff Collaborative Trial Investigators.
Central pressure:variability and impact of cardiovascular risk factors: the Anglo-Cardiff Collaborative Trial Investigators. Hypertension 2008;51(6):1476-82
SEARCH Collaborative Group, Link E, Parish S, Armitage J, Bowman L, Heath S, Matsuda F, Gut I, Lathrop M, Collins R. SLCO1B1 variants and statin-induced myopathy – a genomewide study. N Engl J Med 2008;359(8):789-99
Kinra S, Rameshwar Sarma KV, Ghafoorunissa, Mendu VV, Ravikumar R, Mohan V, Wilkinson IB, Cockcroft JR, Davey Smith G, Ben-Shlomo Y. Effect of integration of supplementational nutrition with public health programmes in pregnancy and early childhood on cardiovascular risk in rural Indian adolescents: long term follow up of Hyderabrad nutrition trial. BMJ 2008 25;337:a605
Schumacher W, Cockcroft J, Timpson NJ, McEniery CM, Gallacher J, Rumley A, Lowe G, Smith GD, Wilkinson IB, Ben-Shlomo Y. Association between C-reactive protein genotype, circulating levels, and aortic pulse wave velocity. Hypertension 2009;53(2):150-7
McEniery CM, McDonnell BJ, So A, Aitken S, Bolton CE, Munnery M, Hickson SS, Yasmin, Maki-Petaga KM, Cockcroft JR Dixon AK, Wilkinson. Aortic calcification is associated with aortic stiffness and isolated systolic hypertension in healthy individuals. Hypertension 2009;53(3):524-31
Bolton CE, Cockcroft JR, Sabit R, Munnery M, McEniery CM, Wilkinson IB, Ebrahim S, Gallacher JE, Shale DJ, Ben-Shlomo Y. Lung function in mid-life compared with later life is a stronger predictor of arterial stiffness in men: the Caerphilly Prospective Study. Int J Epidemiol 2009;38(3):867-76
Pedersen ME, Cockcroft JR. What is the role, if any, for beta-blockers as initial therapy for uncomplicated hypertension? Cur Opin Cardiol 2009;24(4):325-32
Cockcroft JR. Atenolol is dead: long live beta-blockade. J Am Coll Cardiol 2009;253(22)2102
Mackenzie IS, McEniery CM, Dhakam Z, Brown MJ, Cockcroft JR, Wilkinson IB
Comparison of the effects of antihypertensive agents on central blood pressure and arterial stiffness in isolated systolic hypertension. Hypertension 2009;54(2):409-13
Avolio AP, Van Bortel LM, Boutouyri P, Cockcroft JR, McEniery CM, Protogerou AD, Roman MJ, Safar ME, Segers P, Smulyan H. Role of pulse pressure amplification in arterial hypertension: experts' opinion and review of the data. Hypertension 2009;54(2):375-83
Hull JH, Garrod R, Ho TB, Knight RK, Cockcroft JR, Shale DJ, Bolton CE. Increased augmentation index in patients with cystic fibrosis. Eur Respir J 2009;34(6)1322-1328
Hickson SS, Butlin M, Mir FA, Graggaber J, Cheriyan J, Khan F, Grace AA, Yasmin, Cockcroft JR, Wilkinson IB, McEniery CM; Anglo-Cardiff Collaboration Trial Investigators. The accuracy of central SBP determined from the second systolic pack of the peripheral pressure waveform. J Hypertens 2009;27(9):1784-8
Sabit R, Bolton CE, fraser AG, Edwards JM, Edwards PH, Ionescu AA, Cockcroft JR, Shale DJ. Respir Med 2010; 8: 1171-1178
McEniery CM, Spratt M, Munnery M, Yarnell J, Lowe GD, Rumley A, Gallacher J, Ben-shlomo Y, Cockcroft JR, Wilkinson Ib. An analysis of prospective risk factors for aortic stiffness in men: 20 year follow-up from the Caerphilly prospective study.
Hypertension 2010; 56; 36-43
BOOKS
Cockcroft JR, Wilkinson IB, Yki-Jarvinen H. (eds). Type 2 Diabetes as a Vascular Disease. Martin Dunitz London (Commissioned)
Wilkinson IB, Cockcroft JR (eds). Isoloated Systolic Hypertension. Harcourt Brace London
Wilkinson IB, Waring WS, Cockcroft JR. Hypertension: Your Questions Answered. 2003 Churchill Livingstone Edinburgh, UK
Newby DE, Wilkinson IB, Cockcroft JR. Coronary Heart Disease: Your Questions Answered. 2004 Churchill Livingstone Edinburgh, UK. This book was "Highly Commended" in the 2005 BMA Book Prize Competition.
Mackenzie IS, Wilkinson IB, Cockcroft JR. Churchill's Pocketbook of Hypertension 2005 Elsevier Science Edinburgh, UK.
COMMITTEE / EDITORIAL BOARD MEMBERSHIPS
Member of Editorial Board Hypertension Insight
Member of Editorial Board Heart Failure and Hypertension Abstracts
Member of Committee Clinical Section British Pharmacological Society
Member of Education Subcommittee British Pharmacological Society
Honorary Senior Lecturer/Consultant University of Edinburgh
Edinburgh University Wellcome Trust Cardiovascular Research Initiative
Full Member of Molecular Cardiology and Endothelial Cell Biology Board
Member European Working Group Arterial Structure and Function
Member of Bro-Taf Cardiovascular Therapeutics Committee
Investigator SEARCH Study
Sub Group Investigator FIELD Study
Member of Scientific Organising Committee and member of Scientific Faculty
2nd European Meeting on pulse Wave Analysis 1999
Organiser of Type 2 Diabetes and Cardiovascular Risk Discussion Group Meeting 1999
Member of Scientific Organising Committee and member of Scientific Faculty
2nd European Meeting on Pulse Wave Analysis 2001
British Pharmacology Society Regional Lecturer
Member of EC Research Network International Review Panel on Drug Related Problems in the Elderly
Member of the European Council for Blood Pressure and Cardiovascular Research
Member of Scientific Committee First International Consensus Conference on Clinical Applications of Arterial Stiffness. Paris June 16-18th 2000
Representative of The Royal College of Physicians on Cardiology Appointments Committees
Organiser of Type 2 Diabetes and Cardiovascular Risk Discussion Group Meeting 2000
Organiser/Chairman 1st UK Meeting of the Transcranial Doppler Users Group 2001
Member of Scientific Organising Committee and member of Scientific Faculty
3rd European Meeting on Pulse Wave Analysis and Large Artery Function 2001
Honorary Professor in Cardiovascular Disease Prevention University of Nottingham 2004-2008
Honorary Consultant Addenbrooke's Hospital Cambridge 2000-
Organiser Anglo/Dutch Student Exchange Scheme with the University of Mastricht (Dr Ton de Boer) 1998-
Organiser Medical Student Elective Visits University of Sydney Australia and Karolinska Institute Sweden
External Examiner University of Manchester 2001-2005
Internal Examiner Final MB University of Wales College of Medicine
Secretary of the European Association of Clinical Pharmacology and Therapeutics 2003-2007
Organiser ARTERY 4 The Association for Research into Arterial Structure and Physiology Meeting London October 4-5th 2004
Co-organiser 1st Symposium on Exercise Science & Sports Medicine Cardiff 22nd July 2004
Member of University Senate University of Wales Cardiff 2004-
Member of Scientific Steering Committee 2nd, 3rd & 4th International Workshops on The Human Circulation: Non-invasive Haemodynamic, Autonomic and Vascular Monitoring". Graz Austria
Member of Scientific Committee 7th Congress of European Association for Clinical Pharmacology and Therapeutics. Poznan Poland
Member of European Working Group on Cardiovascular Pharmacology and Drug Therapy of the European Society of Cardiology
Organiser ARTERY 5 The Association for Research into Arterial Structure and Physiology Meeting Paris September 30th – October 1st 2005
Organiser 4th British Hypertension Society Master Class Cardiff November 2005
Member of Executive Committee International Society of Vascular Health
CONTRIBUTIONS TO BOOKS
Webb DJ, Benjamin N, Collier JG, Cockcroft JR, Dollery CT, Ritter JM. Local ACE inhibition modulates vascular responses to angiotensin and bradykinin in the human forearm. In: Current advances in ACE inhibition. Sever P, McGregor G (eds). Churchill Livingstone, London 1989; pp 269-275.
Cockcroft JR, Dollery CT. The diuretic dilemma. In: The Handbook of Hypertension Vol 13. Buhler FR, Laragh JH (eds). Elsevier, Amsterdam 1990; pp 202-216.
Cockcroft JR, Webb DJ. Phase I trials on antihypertensive drugs. In: Early phase human drug evaluation. O'Grady J, Linet O, Boobis S (eds). Macmillan, London 1990; pp 302-312.
Cockcroft JR, Webb DJ. Circulating and tissue renin-angiotensin systems and the endothelium. In: The endothelium: An introduction to current research. Warren JW, Alan R (eds). Liss, New York 1990; pp 65-80.
Cockcroft JR, Ritter JM. Pheochromocytoma and related tumours. In: Surgical Endocrinology. Lynn J, Bloom S (eds). Butterworth Heinemann 1993; pp 395-410.
Haynes WG, Cockcroft JR, Morton JJ, Lever AF, Webb DJ. Evidence against a physiological role for a vascular renin-angiotensin system in man. In: Current advances in ACE inhibition 3. Sever P, McGregor G (eds). Churchill Livingstone, London 1993; pp 198-201.
Chowienczyk PJ, Cockcroft JR, Ritter JM. Methacholine induced vasodilation in the human forearm is not inhibited by L-NMMA. In: The Biology of Nitric Oxide. Moncada S, Marletta MA, Hibbs JB, Higgs EA (eds). Portland Press 1994; pp 471- 473.
Cockcroft JR. Coronary heart disease, cholesterol and vitamin E. In: The Experts Speak. The role of nutrition in medicine. Simpson K, Hamilton PA-C (eds). IT Services Sacramento, USA 1997; pp 57-58.
Prasad K, Cockcroft JR. Clinical use of calcium channel antagonists in angina. In: Review of Calcium Channel Antagonists in Hypertension. Heagerty AM (ed). Euromed Communications, Surrey England 1998; pp 33-48.
Cockcroft JR, Goodfellow J. Endothelial dysfunction. In: Diabetes Current Perspectives. Betteridge DJ (ed). Martin Dunitz, London 1999; pp 141-164.
Wilkinson IB, Yki-Jarvinen H, Westerbacka J, Cockcroft JR. Diabetes and arterial stiffness. In: Diabetes and Vascular Disease. Veves A, Johnstone MT (eds). Contemporary Cardiology Series, Humana Press 2001; pp 343-360.
Franklin SS, Wilkinson IB, Cockcroft JR. Brachial and central pulse pressure and cardiovascular risk. In: The Handbook of Hypertension. Safar ME, O'Rourke MF(eds). Elsevier, Amsterdam. (invited contribution In Press)
Yasmin, Cooper DN, Cockcroft JR. Polymorphisms in cardiovascular medicine: the role of genetic variants in disease diagnosis and drug response. In Pharmacogenetics Eds Hall IP, Pirmohamed M.
Cockcroft JR, Wilkinson IB. Does arterial stiffness predict atherosclerotic coronary events? In Advances in Cardiology: "Atherosclerosis, large arteries and cardiovascular risk". Eds Safar ME, Frohlich ED. (invited contribution In Press
