Dr Rebecca Aicheler
Uwch Ddarlithydd mewn Imiwnoleg
Ysgol Chwaraeon a Gwyddorau Iechyd Caerdydd
Cyhoeddiadau Ymchwil
HCMV-secreted glycoprotein gpUL4 inhibits TRAIL-mediated apoptosis and NK cell activation
Vlachava, V. M., Seirafian, S., Fielding, C. A., Kollnberger, S., Aicheler, R. J., Hughes, J., Baker, A., Weekes, M. P., Forbes, S., Wilkinson, G. W. G., Wang, E. C. Y. & Stanton, R. J., 27 Tach 2023, Yn: Proceedings of the National Academy of Sciences of the United States of America. 120, e2309077120.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
The rs2228145 Variant of the Interleukin-6 Receptor (IL-6R) Gene Impacts on In Vitro Cellular Responses to SARS-CoV-2 VOC B1.1.7 Recombinant Spike Protein
Sarwar, S., Aicheler, R., Butcher, L., Rees, K., Potter, S., Rowlands, R. & Webb, R., 3 Hyd 2023, Yn: COVID. 3, 10, t. 1554-1570 17 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
IL-6 signaling in acute exercise and chronic training: Potential consequences for health and athletic performance
Nash, D., Hughes, M. G., Butcher, L., Aicheler, R., Smith, P., Cullen, T. & Webb, R., 8 Hyd 2022, Yn: Scandinavian Journal of Medicine and Science in Sports. 33, 1, t. 4-19 16 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl adolygu › adolygiad gan gymheiriaid
Monoclonal antibodies targeting nonstructural viral antigens can activate ADCC against human cytomegalovirus
Vlahava, V. M., Murrell, I., Zhuang, L., Aicheler, R. J., Lim, E., Miners, K. L., Ladell, K., Suárez, N. M., Price, D. A., Davison, A. J., Wilkinson, G. W. G., Wills, M. R., Weekes, M. P., Wang, E. C. Y. & Stanton, R. J., 15 Chwef 2021, Yn: Journal of Clinical Investigation. 131, 4, e139296.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Downregulation of HLA-I by the molluscum contagiosum virus mc080 impacts NK-cell recognition and promotes CD8+ T-cell evasion
Elasifer, H., Wang, E. C. Y., Prod’homme, V., Davies, J., Forbes, S., Stanton, R. J., Patel, M., Fielding, C. A., Roberts, D., Traherne, J. A., Gruber, N., Bugert, J. J., Aicheler, R. J. & Wilkinson, G. W. G., 8 Meh 2020, Yn: Journal of General Virology. 101, 8, t. 863-872 10 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation
Fielding, C. A., Weekes, M. P., Nobre, L. V., Ruckova, E., Wilkie, G. S., Paulo, J. A., Chang, C., Suárez, N. M., Davies, J. A., Antrobus, R., Stanton, R. J., Aicheler, R. J., Nichols, H., Vojtesek, B., Trowsdale, J., Davison, A. J., Gygi, S. P., Tomasec, P., Lehner, P. J. & Wilkinson, G. W. G., 10 Chwef 2017, Yn: eLife. 6, e22206.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Human cytomegalovirus: taking the strain
Wilkinson, G. W. G., Davison, A. J., Tomasec, P., Fielding, C. A., Aicheler, R., Murrell, I., Seirafian, S., Wang, E. C. Y., Weekes, M., Lehner, P. J., Wilkie, G. S. & Stanton, R. J., 17 Ebr 2015, Yn: Medical Microbiology and Immunology. 204, 3, t. 273-284 12 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl adolygu › adolygiad gan gymheiriaid
HCMV pUL135 remodels the actin cytoskeleton to impair immune recognition of infected cells
Stanton, R. J., Prod'Homme, V., Purbhoo, M. A., Moore, M., Aicheler, R. J., Heinzmann, M., Bailer, S. M., Haas, J., Antrobus, R., Weekes, M. P., Lehner, P. J., Vojtesek, B., Miners, K. L., Man, S., Wilkie, G. S., Davison, A. J., Wang, E. C. Y., Tomasec, P. & Wilkinson, G. W. G., 13 Awst 2014, Yn: Cell Host and Microbe. 16, 2, t. 201-214 14 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Quantitative temporal viromics: An approach to investigate host-pathogen interaction
Weekes, M. P., Tomasec, P., Huttlin, E. L., Fielding, C. A., Nusinow, D., Stanton, R. J., Wang, E. C. Y., Aicheler, R., Murrell, I., Wilkinson, G. W. G., Lehner, P. J. & Gygi, S. P., 5 Meh 2014, Yn: Cell. 157, 6, t. 1460-1472 13 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Two Novel Human Cytomegalovirus NK Cell Evasion Functions Target MICA for Lysosomal Degradation
Fielding, C. A., Aicheler, R., Stanton, R. J., Wang, E. C. Y., Han, S., Seirafian, S., Davies, J., McSharry, B. P., Weekes, M. P., Antrobus, P. R., Prod'homme, V., Blanchet, F. P., Sugrue, D., Cuff, S., Roberts, D., Davison, A. J., Lehner, P. J., Wilkinson, G. W. G. & Tomasec, P., Mai 2014, Yn: PLoS Pathogens. 10, 5, e1004058.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid